Publications

Check out our full publication list on pubmed! Here are some recent papers from our group:

2025

Exploring Centiloid Robustness: Impact of Sample Size and Image Resolution on Centiloid Conversion Accuracy. Zhang J, Soleimani-Meigooni DN, Koeppe R, Ackley S, Schonhaut DR, Lin ZE, Maiti P, Yballa C, Rocha S, Shankar R, Amuiri A, Bourgeat P, Doré V, Carrillo MC, Dickerson BC, Apostolova LG, Harrison TM, Grinberg LT, Spina S, Seeley WW, Rabinovici GD, La Joie R, Blazhenets G; LEADS Consortium and Alzheimer’s Disease Neuroimaging Initiative. J Nucl Med. 2025 Oct 23:jnumed.125.270607. doi: 10.2967/jnumed.125.270607. Online ahead of print. PMID: 41130790

Calibration of multisite raters for prospective visual reads of amyloid PET scans. Soleimani-Meigooni DN*, Pezzoli S* (co-first), Blazhenets G, La Joie R, Lin Z, Soppe CL, Johnson DR, Koran MEI, McConathy JE, Nasrallah IM, Ponisio MR, Tanner JA, Villemagne VL, Windon CC, Zeineh M, Biber S, Kukull WA, O'Connell H, Peterson DJ, Mormino EC, Johnson SC, Rabinovici GD; LEADS Consortium; PREVENT‐AD Research Group; Alzheimer's Disease Neuroimaging Initiative. Alzheimers Dement. 2025 Oct;21(10):e70732. doi: 10.1002/alz.70732. PMID: 41030129

Regional tau PET patterns predict prospective domain-specific cognitive decline in early symptomatic Alzheimer's disease. Malpetti M, Rathore S, Iaccarino L, La Joie R, Tronchin G, Wessels AM, Sims JR, Pontecorvo MJ, Shcherbinin S, Rabinovici GD. Alzheimers Res Ther. 2025 Oct 6;17(1):220. doi: 10.1186/s13195-025-01868-7. PMID: 41053874

Concordance Between Amyloid-PET Quantification and Real-World Visual Reads. Zeltzer E, Schonhaut DR, Mundada NS, Blazhenets G, Soleimani-Meigooni DN, Cho H, Ranasinghe KG, Windon C, Yadollahikhales G, Apgar C, Gatsonis C, Carrillo MC, Hanna L, Romanoff J, Hillner BE, Koeppe RA, March A, Siegel BA, Smith K, Whitmer RA, Iaccarino L, Rabinovici GD, La Joie R. JAMA Neurol. 2025 Sep 1;82(9):952-962. doi: 10.1001/jamaneurol.2025.2218. PMID: 40720133

Amyloid PET and clinical management in a diverse, cognitively impaired population: The New IDEAS Study. Windon CC, Gatsonis C, Carrillo MC, Romanoff J, Hanna L, Glavin E, Gareen I, Gutman R, Hillner BE, March A, O'Bryant S, Rissman RA, Siegel BA, Smith K, Whitmer RA, Weber CJ, Wilkins CH, Dilworth-Anderson P, Rabinovici GD. Alzheimers Dement. 2025 Jul;21(7):e70504. doi: 10.1002/alz.70504. PMID: 40728069 

Sex differences in amyloid PET in a large, real-world sample from the Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study. Abu Raya M, Zeltzer E, Blazhenets G, Schonhaut DR, Allen IE, Carrillo MC, Gatsonis C, Hanna L, Hillner BE, Iaccarino L, March A, Mundada NS, Perez JM, Smith K, Yballa C, Siegel BA, Windon C, Whitmer RA, Kaitlin C, La Joie R, Rabinovici GD. Alzheimers Dement. 2025 May;21(5):e70304. doi: 10.1002/alz.70304. PMID: 40415175

Amyloid PET in Sporadic Early- Versus Late-Onset Alzheimer's Disease: Comparison of the LEADS and ADNI Cohorts. Lagarde J, Maiti P, Schonhaut DR, Blazhenets G, Zhang J, Eloyan A, Thangarajah M, Taurone A, Allen IE, Soleimani-Meigooni DN, Zeltzer E, Windon C, Abu Raya M, Vrillon A, Smith K, Shankar R, Amuiri A, Rocha S, Hammers DB, Dage JL, Nudelman KN, Kirby K, Aisen P, Koeppe R, Landau SM, Carrillo MC, Touroutoglou A, Brickhouse M, Vemuri P, Beckett L, Raman R, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu JC, Mendez MF, Womack K, Musiek E, Onyike CU, Riddle M, Grant IM, Rogalski E, Johnson ECB, Salloway S, Sha S, Turner RS, Wingo TS, Wolk DA, Dickerson BC, Apostolova LG, La Joie R*, Rabinovici GD* (co-last); LEADS Consortium for the Alzheimer's Disease Neuroimaging Initiative. Ann Neurol. 2025 Mar 17. doi: 10.1002/ana.27233. Online ahead of print. PMID: 40091774

(18)F-MK-6240 tau PET in patients at-risk for chronic traumatic encephalopathy. Alosco ML, Mejía Pérez J, Culhane JE, Shankar R, Nowinski CJ, Bureau S, Mundada N, Smith K, Amuiri A, Asken B, Groh JR, Miner A, Pettway E, Mosaheb S, Tripodis Y, Windon C, Mercier G, Stern RA, Grinberg LT, Soleimani-Meigooni DN, Christian BT, Betthauser TJ, Stein TD, McKee AC, Mathis CA, Abrahamson EE, Ikonomovic MD, Johnson SC, Mez J, La Joie R, Schonhaut D, Rabinovici GD. Mol Neurodegener. 2025 Feb 25;20(1):23. doi: 10.1186/s13024-025-00808-1. PMID: 39994806

Role of tau versus TDP-43 pathology on medial temporal lobe atrophy in aging and Alzheimer's disease. Wisse LEM, Wuestefeld A, Murray ME, Jagust W, La Joie R. Alzheimers Dement. 2025 Feb;21(2):e14582. doi: 10.1002/alz.14582. PMID: 39985478

2024

Head-to-Head Comparison of Tau and Amyloid Positron Emission Tomography Visual Reads for Differential Diagnosis of Neurodegenerative Disorders: An International, Multicenter Study. Soleimani-Meigooni DN, Smith R, Provost K, Lesman-Segev OH, Allen IE, Chen MK, Cho H, Edwards L, Janelidze S, La Joie R, Mundada N, Ossenkoppele R, Stomrud E, Strandberg O, Strom A, Boxer AL, Dage JL, Gorno-Tempini ML, Kramer JH, Miller BL, Rojas JC, Rosen HJ, Lyoo CH, Hansson O, Rabinovici GD. Ann Neurol. 2024 Sep;96(3):476-487. doi: 10.1002/ana.27008. Epub 2024 Jun 18. PMID: 38888212

Molecular neuroimaging in dominantly inherited versus sporadic early-onset Alzheimer's disease. Iaccarino L*, Llibre-Guerra JJ* (co-first), McDade E, Edwards L, Gordon B, Benzinger T, Hassenstab J, Kramer JH, Li Y, Miller BL, Miller Z, Morris JC, Mundada N, Perrin RJ, Rosen HJ, Soleimani-Meigooni D, Strom A, Tsoy E, Wang G, Xiong C, Allegri R, Chrem P, Vazquez S, Berman SB, Chhatwal J, Masters CL, Farlow MR, Jucker M, Levin J, Salloway S, Fox NC, Day GS, Gorno-Tempini ML, Boxer AL, La Joie R, Bateman R*, Rabinovici GD* (co-last). Brain Commun. 2024 May 3;6(3):fcae159. doi: 10.1093/braincomms/fcae159. eCollection 2024. PMID: 38784820

Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias. Asken BM, Tanner JA, Vandevrede L, Apple A, Chapleau M, Gaynor LS, Lane-Donovan C, Lenio S, Yadollahikhales G, Lee S, Gontrum E, Knudtson M, Iaccarino L, La Joie R, Cobigo Y, Staffaroni AM, Casaletto KB, Gardner RC, Grinberg LT, Gorno-Tempini ML, Rosen HJ, Seeley WW, Miller BL, Kramer J, Rabinovici GD. Neurology. 2024 Apr 9;102(7):e209183. doi: 10.1212/WNL.0000000000209183. Epub 2024 Mar 15. PMID: 38489566

Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis. Chapleau M*, La Joie R* (co-first), Yong K, Agosta F, Allen IE, Apostolova L, Best J, Boon BDC, Crutch S, Filippi M, Fumagalli GG, Galimberti D, Graff-Radford J, Grinberg LT, Irwin DJ, Josephs KA, Mendez MF, Mendez PC, Migliaccio R, Miller ZA, Montembeault M, Murray ME, Nemes S, Pelak V, Perani D, Phillips J, Pijnenburg Y, Rogalski E, Schott JM, Seeley W, Sullivan AC, Spina S, Tanner J, Walker J, Whitwell JL, Wolk DA, Ossenkoppele R, Rabinovici GD; PCA International Work Group. Lancet Neurol. 2024 Feb;23(2):168-177. doi: 10.1016/S1474-4422(23)00414-3. PMID: 38267189

2023

[18F]PI-2620 Binding Patterns in Patients with Suspected Alzheimer Disease and Frontotemporal Lobar Degeneration. Blazhenets G*, Soleimani-Meigooni DN* (co-first), Thomas W, Mundada N, Brendel M, Vento S, VandeVrede L, Heuer HW, Ljubenkov P, Rojas JC, Chen MK, Amuiri AN, Miller Z, Gorno-Tempini ML, Miller BL, Rosen HJ, Litvan I, Grossman M, Boeve B, Pantelyat A, Tartaglia MC, Irwin DJ, Dickerson BC, Baker SL, Boxer AL, Rabinovici GD, La Joie R. J Nucl Med. 2023 Dec 1;64(12):1980-1989. doi: 10.2967/jnumed.123.265856. PMID: 37918868

Amyloid Positron Emission Tomography and Subsequent Health Care Use Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia. Rabinovici GD, Carrillo MC, Apgar C, Gareen IF, Gutman R, Hanna L, Hillner BE, March A, Romanoff J, Siegel BA, Smith K, Song Y, Weber C, Whitmer RA, Gatsonis C. JAMA Neurol. 2023 Nov 1;80(11):1166-1173. doi: 10.1001/jamaneurol.2023.3490. PMID: 37812437

Amyloid and tau-PET in early-onset AD: Baseline data from the Longitudinal Early-onset Alzheimer's Disease Study (LEADS). Cho H*, Mundada NS* (co-first), Apostolova LG, Carrillo MC, Shankar R, Amuiri AN, Zeltzer E, Windon CC, Soleimani-Meigooni DN, Tanner JA, Heath CL, Lesman-Segev OH, Aisen P, Eloyan A, Lee HS, Hammers DB, Kirby K, Dage JL, Fagan A, Foroud T, Grinberg LT, Jack CR, Kramer J, Kukull WA, Murray ME, Nudelman K, Toga A, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Riddle M, Rogalski EJ, Salloway S, Sha S, Turner RS, Wingo TS, Wolk DA, Koeppe R, Iaccarino L, Dickerson BC, La Joie R*, Rabinovici GD* (co-last); LEADS Consortium. Alzheimers Dement. 2023 Nov;19 Suppl 9(Suppl 9):S98-S114. doi: 10.1002/alz.13453. Epub 2023 Sep 10. PMID: 37690109

Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment. Mundada NS, Rojas JC, Vandevrede L, Thijssen EH, Iaccarino L, Okoye OC, Shankar R, Soleimani-Meigooni DN, Lago AL, Miller BL, Teunissen CE, Heuer H, Rosen HJ, Dage JL, Jagust WJ, Rabinovici GD, Boxer AL, La Joie R. Alzheimers Res Ther. 2023 Sep 22;15(1):157. doi: 10.1186/s13195-023-01302-w. PMID: 37740209

Alzheimer's pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome. Asken BM, Tanner JA, Gaynor LS, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, Fonseca C, Shankar R, Grant H, Smith K, Lago AL, Xu H, La Joie R, Cobigo Y, Rosen H, Perry DC, Rojas JC, Miller BL, Gardner RC, Wang KKW, Kramer JH, Rabinovici GD. Alzheimers Res Ther. 2023 Jul 21;15(1):126. doi: 10.1186/s13195-023-01275-w. PMID: 37480088 

AD and non-AD mediators of the pathway between the APOE genotype and cognition. Nichols E, Brickman AM, Casaletto KB, Dams-O'Connor K, George KM, Kumar RG, Palta P, Rabin JS, Satizabal CL, Schneider J, Pa J, La Joie R. Alzheimers Dement. 2023 Jun;19(6):2508-2519. doi: 10.1002/alz.12885. Epub 2022 Dec 14. PMID: 36516004