Wepnyu (Yembe) Njamshi completed his fellowship in Brain Health Equity at GBHI a few months ago, and the paper he worked on while at UCSF was just published today in Alzheimer's & Dementia.
In this paper, Yembe looked at the Tablet based cognitive (TabCAT) assessment available in the Longitudinal Early Onset Alzheimer's Disease Study (LEADS) cohort, including 475 participants across 16 sites in the US. Analyses investigated the validity of 4 TabCAT tests (focusing on executive functions and visuo-spatial abilities) on 3 different levels
- convergent validity, i.e. associations with pen-and-paper tests from the UDS3 battery and a few other tests
- diagnostic validity, i.e. ability to distinguish clinical group, or in the impaired participants, those who are amyloid-PET positive versus negative
- neuroanatomical validity, i.e. correlation with patterns of tau-PET signal, expecting patterns of associations reflecting known brain–behavior relationships
Check out the paper for details on the results!
Now that Yembe has returned to his home country of Cameroon, he will be working on adapting TabCAT to be used there!
